BRIDGE AND FRAGMENT ABERRATIONS IN PODOPHYLLUM PELTATUM
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چکیده
منابع مشابه
Assessment of Genetic Diversity in Podophyllum peltatum by Molecular Markers*
The quality and quantity of medicinal plants are serious issues for the pharmaceutical and dietary supplement industries. Traditionally, this material has been harvested from the wild, and while cultivation procedures have been developed for supplements such as St. John’s Wort, this is still the general method employed for the majority of medicinal plants. Increasing public demand for these pro...
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Human blood neutrophil granulocytes (neutrophils) treated with Podophyllum peltatum L.-derived compounds exhibited an enhanced oxidative response to subsequent challenge with bacterial formyl peptides. This priming effect was concerned with superoxide anion (O2-) release (respiratory burst). The phenomenon was observed with a potentized preparation containing, among other things, podophyllum ex...
متن کاملPodophyllum Peltatum and Observations on the Creek and Cherokee Indians: William Bartram’s Preservation of Native American Pharmacology
Historians have examined the significant contributions John and William Bartram made to 18th- and 19th-century knowledge of indigenous North American flora. However, the Bartrams' contribution to medicinal botanical knowledge, particularly William Bartram's compilation of Indians' knowledge on the preparation and use of medicinal botanicals, is not well-known. In addition, while William Bartram...
متن کاملHigh yield of podophyllotoxin from leaves of Podophyllum peltatum by in situ conversion of podophyllotoxin 4- O-beta-D-glucopyranoside.
Rehydration of powdered tissues of Podophyllum peltatum L. prior to extraction with an organic solvent allows endogenous beta-glucosidases to hydrolyze lignan 4-O-beta-D-glucosides in situ and increase the yield of podophyllotoxin. Aqueous extraction of rhizomes and leaves of P. peltatum yielded 4- to 10-fold greater quantities of podophyllotoxin than the traditional ethanolic extraction. Most ...
متن کاملNext generation sequencing in predicting gene function in podophyllotoxin biosynthesis.
Podophyllum species are sources of (-)-podophyllotoxin, an aryltetralin lignan used for semi-synthesis of various powerful and extensively employed cancer-treating drugs. Its biosynthetic pathway, however, remains largely unknown, with the last unequivocally demonstrated intermediate being (-)-matairesinol. Herein, massively parallel sequencing of Podophyllum hexandrum and Podophyllum peltatum ...
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ژورنال
عنوان ژورنال: Genetics
سال: 1966
ISSN: 1943-2631
DOI: 10.1093/genetics/53.1.55